Searching for SNPs with cloud computing
| Title | Searching for SNPs with cloud computing |
| Publication Type | Journal Articles |
| Year of Publication | 2009 |
| Authors | Langmead B, Schatz MC, Jimmy L, Pop M., Salzberg SL |
| Journal | Genome BiologyGenome Biology |
| Volume | 10 |
| Type of Article | 10.1186/gb-2009-10-11-r134 |
| ISBN Number | 1465-6906 |
| Abstract | As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the SNP caller SOAPsnp. Executing in parallel using Hadoop, Crossbow analyzes data comprising 38-fold coverage of the human genome in three hours using a 320-CPU cluster rented from a cloud computing service for about $85. Crossbow is available from http://bowtie-bio.sourceforge.net/crossbow/. |